Bio Farma director says there are three candidate vaccines targeted by government

REPUBLIKA.CO.ID, JAKARTA – President Joko Widodo (Jokowi) has instructed the Minister of Health to immediately prepare for the implementation of monkeypox vaccination. The government is trying to provide monkeypox or monkeypox vaccination in the country, as a strategy to deal with monkeypox disease.

director president Organic Farm Honesti Basyir said the government is targeting three vaccine candidates, namely Imvamune® (Northern Bavarian Denmark), LC16M8 (SVRG Kaketsuken Japan) and ACAM2000 (Sanofi Pasteur). “There are several candidates monkeypox vaccine which we discussed with them, namely Imvamune® (Northern Bavarian Denmark), 2,000 doses were imported by the Ministry of Health,” Honesty said in RDP with Commission IX, Tuesday (8/30/2022).

According to Honesty, all three types of vaccines come from attenuated viruses. As for Imvamune® (Northern Bavarian Denmark), it is administered to the age group above 18 years with indications of smallpox, Monkeypox Orthopoxvirus. The technology used is also Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN). At the moment stock availability is still limited.

The administration of two doses is simplified into a single dose. The vaccine has been used in the United States and Canada. Administration is preferred for post-exposure prophylaxis (PEP). This treatment is generally carried out after the occurrence of acts likely to cause monkeypox.

The second vaccine is LC16M8 (SVRG Kaketsuken Japan). This vaccine from Japan is given for smallpox. Kaketsuken produces only for national stock. The bulk production capacity of 30 million doses will be increased to 80 million doses.

The vaccine form is freeze-dried and stable for up to 30 days after reconstitution. Administration is preferred for post-exposure prophylaxis (PEP). This treatment is generally carried out after the occurrence of acts likely to cause monkeypox.

Then the third vaccine is ACAM2000 (Sanofi Pasteur). Vaccination for the age group over one year for smallpox indications. The administration of the vaccine is a single dose and already has an FDA license.

However, this vaccine cannot be given to people with heart disease and immunosuppression. Administration is preferred for post-exposure prophylaxis (PEP). This treatment is generally carried out after the occurrence of acts that risk causing monkey pox.

In addition to requesting the purchase of vaccines monkey poxJokowi also instructed his staff to strictly inspect each arrival at various entrances to the country as well as high-interaction locations. However, he asked the public not to panic over the discovery of this case. Because, Jokowi said, monkeypox is transmitted through direct contact, not droplets.